Table 2.
GO analysis of the candidate miRNAs in TRD
| Term | Overlap | P-values |
|---|---|---|
| Axon part (GO:0033267) | 32/415 | 0.003757 |
| CHD-type complex (GO:0090545) | 4/18 | 0.008459 |
| Cytoplasmic ribonucleoprotein granule (GO:0036464) | 23/268 | 0.003642 |
| Early endosome (GO:0005769) | 34/434 | 0.002231 |
| NuRD complex (GO:0016581) | 4/18 | 0.008459 |
| PML body (GO:0016605) | 13/113 | 0.002301 |
| Postsynaptic density (GO:0014069) | 25/35 | 0.006811 |
| Ribonucleoprotein granule (GO:0035770) | 23/281 | 0.006435 |
| Transcription factor complex (GO:0005667) | 33/403 | 0.001257 |
| Transcriptional repressor complex (GO:0017053) | 11/90 | 0.003031 |
| Appendage development (GO:0048736) | 23/188 | 0.000026 |
| Axonogenesis (GO:0007409) | 46/498 | 0.000010 |
| Cell fate commitment (GO:0045165) | 34/304 | 0.000003 |
| Embryonic organ development (GO:0048568) | 43/480 | 0.000041 |
| Limb development (GO:0060173) | 23/188 | 0.000026 |
| Lung development (GO:0030324) | 23/193 | 0.000040 |
| Positive regulation of neuron differentiation (GO:0045666) | 41/402 | 0.000003 |
| Positive regulation of neuron projection development (GO:0010976) | 32/304 | 0.000018 |
| Regulation of cellular component size (GO:0032535) | 39/407 | 0.000021 |
| Regulation of transcription involved in cell fate commitment (GO:0060850) | 7/18 | 0.000010 |
| DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228) | 46/479 | 0.000009 |
| GTP binding (GO:0005525) | 33/406 | 0.002841 |
| Guanyl nucleotide binding (GO:0019001) | 35/429 | 0.002028 |
| Guanyl ribonucleotide binding (GO:0032561) | 35/429 | 0.002028 |
| Nucleoside binding (GO:0001882) | 33/422 | 0.005119 |
| Purine nucleoside binding (GO:0001883) | 33/414 | 0.003839 |
| Purine ribonucleoside binding (GO:0032550) | 33/411 | 0.003434 |
| Ribonucleoside binding (GO:0032549) | 33/415 | 0.003982 |
| SUMO transferase activity (GO:0019789) | 5/20 | 0.002265 |
| Transcription corepressor activity (GO:0003714) | 22/195 | 0.000214 |