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. Author manuscript; available in PMC: 2021 Aug 21.
Published in final edited form as: Am J Med Genet A. 2020 Nov 27;185(2):413–423. doi: 10.1002/ajmg.a.61977

Table 4:

Developmental milestones overall, and both MFDM patients aged 2 years and older, and 5 years and older

Skill Overall
n=47
Ages 2yo +
n=42
Ages 5yo +
n=24
Achieved, (%) Average age Achieved, (%) Achieved, (%)
Gross motor Sitting with support 43/44, (97.7%) 7 mo 38/39, (97.4%) 21/22, (95.5%)
Crawling 39/42, (92.9%) 14.1 mo 37/38, (97.4%) 22/22, (100%)
Walking 37/45, (82.2%) 21.4 mo 37/40, (92.5%) 22/22, (100%)
Stairs 33/44, (75.0%) 3.3 yr 33/39, (84.6%) 21/22, (95.5%)
Fine motor Reaches for objects 44/44 (100%) 8.3 mo 39/39, (100%) 22/22, (100%)
Scribbles 38/44 (86.4%) 29.5 mo 38/39, (97.4%) 21/22, (95.5%)
Uses utensils 33/43 (76.7%) 3.2 yr 33/38, (86.8%) 21/21, (100%)
Dresses self 16/45 (35.6%) 6 yr 16/40, (40%) 14/23, (60.9%)
Communication Single words 34/44 (77.3%) 34 mo 34/39, (87.2%) 21/22, (95.5%)
Signs 28/43 (65.1%) 27.9 mo 28/38, (73.7%) 15/21, (71.4%)
Communication device 9/42 (21.4%) 3.7 yr 9/37, (24.3%) 4/20, (25.0%)
Points 33/43 (76.7%) 21.3 mo 33/38, (86.8%) 18/21, (85.7%)

MFDM = mandibulofacial dysostosis with microcephaly, mo = months, yr = years