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. 2021 Aug 12;118(33):e2107558118. doi: 10.1073/pnas.2107558118

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Copyright © 2021 the Author(s). Published by PNAS.

This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).

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Fig. 2. — Differential accessibility regions (DARs) in response to phosphate starvation. (A) Pie chart representing the total number of upDARs and downDARs. (B) Percentage of upDARs and downDARs as a function of gene region. (C) IPS1 exhibits two upDARs in response to phosphate limitation. (D) PHR1 shows no changes in its chromatin accessibility in response to low Pi. (E) The chromatin at the NR1 locus becomes less accessible in response to Pi limitation. From the Top to Bottom, tracks represent locus organization, with the arrow indicating direction of transcription; red differential signal, greater accessibility; blue differential signal, lower accessibility; red lines, upDARs; blue lines, downDARs; green, +P accessibility profile; and purple, –P accessibility profile. Signal was group-scaled. (F) Gene Ontology (GO) enrichment analysis of genes associated with upDARs in response to phosphate limitation. Values represent adjusted P values.