Fig. 2.

B cells from young and elderly HIV individuals, as compared to those from age-matched healthy controls, are characterized by higher expression of pro-inflammatory markers. B cells were isolated by magnetic sorting from the blood of young and elderly HIV individuals, and from age-matched healthy controls. B cells were left unstimulated, the RNA was extracted and qPCR performed to evaluate RNA expression of pro-inflammatory cytokines (a), pro-inflammarory miRs (b) and cell cycle inhibitors (c). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001