TABLE 1.
Donor and Recipient Characteristics of SLKT Recipients Over 3 Eras
| Characteristic | August 10, 2007-August 10, 2012 (n = 1974) | August 11, 2012-August 10, 2017 (n = 3124) | August 11, 2017-June 12, 2019 (n = 1234) | P Value |
|---|---|---|---|---|
| Donor age, years | 34 (22–47) | 33 (23–46) | 34 (25–46) | 0.45 |
| ECD | 193 (9.8) | 255 (8.2) | 88 (7.1) | 0.02 |
| KDPI, % | 30 (12–54) | 29 (12–51) | 31 (14–53) | 0.02 |
| KDPI >85% | 85 (4.6) | 101 (3.4) | 34 (2.8) | 0.03 |
| KDRI-Rao | 1.05 (0.88–1.33) | 1.04 (0.87–1.29) | 1.06 (0.89–1.31) | 0.01 |
| Recipient age, years | 56 (50–61) | 58 (51–63) | 58 (51–64) | <0.001 |
| Female recipient | 706 (35.8) | 1139 (36.5) | 493 (40.0) | 0.04 |
| Recipient race/ethnicity* | 0.01 | |||
| White | 1266 (64.0) | 2001 (64.0) | 757 (61.4) | |
| African American | 294 (14.9) | 468 (15.0) | 182 (14.8) | |
| Hispanic | 310 (15.7) | 520 (16.6) | 218 (17.7) | |
| Diagnosis | <0.001 | |||
| HCV | 493 (26.9) | 638 (21.0) | 155 (13.0) | |
| Alcohol-related cirrhosis | 292 (15.9) | 589 (19.4) | 303 (25.3) | |
| NASH | 186 (7.9) | 501 (16.5) | 269 (21.7) | |
| HCC | 172 (9.4) | 302 (10.0) | 97 (8.1) | |
| Recipient BMI ≥35 kg/m2 | 216 (10.9) | 355 (11.4) | 146 (11.8) | 0.74 |
| Dialysis while on waiting list | 1364 (68.9) | 2177 (69.6) | 880 (71.3) | 0.47 |
| GFR <25 mL/min at transplant | 274 (14.5) | 456 (15.2) | 197 (16.3) | P = 0.01 |
| GFR ≥25 and <50 mL/min at transplant | 231 (12.3) | 348 (11.6) | 121 (10.0) | |
| GFR ≥50 mL/min at transplant | 109 (5.8) | 144 (4.8) | 36 (3.0) | |
| GFR at transplant, mL/min | 27.0 (18.8–40.4) | 25.7 (17.2–36.5) | 22.8 (16.9–32.5) | 0.02 |
| Graft travel distance, miles | 42 (5–118) | 72 (9–195.5) | 77 (12–216) | <0.001 |
| Cold ischemic time, hours | 6.4 (5.0–8.0) | 6.1 (4.9–7.8) | 5.9 (4.7–7.3) | <0.001 |
NOTE: Data are shown as n (%) or median (IQR).
*
Race/ethnicity summary categories do not include Asian/Pacific Islander, Native American, Other.