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. 2021 Aug 17;13:817–857. doi: 10.2147/JEP.S236743

Figure 1.

Figure 1

Physiopathological mechanisms of pulmonary arterial hypertension.

Abbreviations: ↑, increase in; ECs, endothelial cells; EGF, epidermal growth factor; FGF, fibroblast growth factor IL, interleukin; PDGF, platelet-derived growth factor RAAS, renin–angiotensi–-aldosterone system; SMCs, smooth muscle cells; VEGF, vascular endothelial growth factor; VIP, vasoactive intestinal peptide.