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. Author manuscript; available in PMC: 2021 Aug 21.
Published in final edited form as: J Am Soc Mass Spectrom. 2021 Apr 5;32(6):1300–1311. doi: 10.1021/jasms.0c00451

Table 1.

Top 15 most abundant histone codes quantified in each condition (average ± standard deviation of three replicates). The figure (the upper-right corner) showed the changes of relative abundance for the most abundant histone code K9me2K27me3 in distinct cell cycle phases.

Histone code H3.1_Asy Histone code H3.2_Asy graphic file with name nihms-1719121-t0008.jpg
K9me2K27me3 7% ± 1.4% K9me2K27me3 11% ± 3.0%
K9me2K27me1K36me1 7% ± 1.5% K9me1K14me1K27me2 11% ± 2.6%
K9me2R42me2 5% ± 5.4% K9me2K27me1K36me1 6% ± 1.2%
K9me1K14me1K27me2 4% ± 1.0% R17me2K27me2 4% ± 0.7%
K9me2K23acK27me1K36me1 4% ± 3.4% K9me2K14acK27me3 3% ± 1.0%
R17me2K27me2 3% ± 1.0% K9me2K23acK27me3 3% ± 1.2%
K9me1K14me1K23acK27me2 3% ± 0.8% K9me1K14me1K23acK27me2 3% ± 0.3%
K9me2K14acK27me3 2% ± 1.2% K9me1K14me1K27me2K36me2 3% ± 1.0%
K9me2K23acK27me3 2% ± 1.9% K9me1K14me1K18acK27me2 2% ± 1.0%
K9me1K14me1K18acK27me2 2% ± 0.8% K9me2K18acK27me3 2% ± 0.5%
K9me1R17me1K27me2 2% ± 1.2% K14me2K27me3 2% ± 0.4%
K9me2K18acK27me3 2% ± 1.5% K9me1R17me1K27me2 2% ± 0.6%
K9me2K18acK23acK27me1K36me1 2% ± 0.8% K27me3 2% ± 1.0%
K14me2K27me3 2% ± 0.6% K9me2K23acK27me1K36me1 1% ± 0.9%
K9me2K23acK27ac 2% ± 0.6% K9me2K27me3K36me1 1% ± 0.1%
Histone code H3.1_G1 Histone code H3.1_S Histone code H13.1_M
K9me2K27me3 29% ± 5.1% K9me2K27me3 32% ± 5.4% K9me2K27me3 10% ± 5.5%
K9me2K23acK27me3 6% ± 1.2% K9me2K23acK27me3 7% ± 0.7% K9me2S10phK23me1K27me1 6% ± 1.7%
K9me2K23acK27me1K36me1 4% ± 2.3% K9me2K27me3K36me1 5% ± 1.2% K9me2S10phK27me3 6% ± 1.3%
K9me2K27me1K36me1 4% ± 0.5% K9me2K23acK27me1K36me1 4% ± 0.9% K9me2S10phK27me1K36me1 3% ± 1.2%
K9me2K27me3K36me1 3% ± 1.9% K9me2K27me1K36me1 3% ± 1.0% K9me1K14me1K27me2 3% ± 2.2%
K9me2K36me3 3% ± 1.4% K9me1K14me1K27me2K36me2 3% ± 1.7% K9me2S10phK23acK27ac 3% ± 1.8%
K9me1K14me1K27me2 3% ± 1.1% K9me1K14me1K27me2 3% ± 0.9% K9me1K14me1K23acK27me2 3% ± 2.0%
K9me2K27me1K36me3 3% ± 1.2% K9me1K14me1K27me3 2% ± 0.9% K9me2K23acK27me1K36me1 3% ± 1.5%
K9me1K14me1K23acK27me2 3% ± 1.4% K9me2K27me1K36me3 2% ± 1.5% K9me2K27me3K36me1 2% ± 1.0%
K9me2K18acK27me3 2% ± 0.6% K9me2K14acK18acK27me3 2% ± 0.3% K9me3S10phK23me2K27me2 2% ± 1.2%
K27me3 2% ± 1.3% K9me2K36me3 2% ± 0.7% K9me2K36me3 2% ± 1.7%
K9me1K14me1K27me2K36me2 2% ± 0.7% K9me2K18acK27me3 2% ± 0.7% K9me2K27ac 2% ± 0.6%
K9me3K27me2K36me2 1% ± 0.5% K27me3 2% ± 0.9% K9me3S10phK27me2 2% ± 1.1%
K9me1K14me1K27me3 1% ± 0.6% K9me2K18acK23acK27me1K36me1 2% ± 0.5% K9me2S10phR26me2 2% ± 0.9%
K9me2K27me1R40me2 1% ± 1.0% K9me2K18acK23acK27me3 2% ± 0.4% K9me2K18acK27me1K36me1 2% ± 0.8%
Histone code H3.2_G1 Histone code H3.2_S Histone code H3.2_M
K9me2K27me3 29% ± 3.7% K9me2K27me3 30% ± 3.2% K9me2K27me3 14% ± 1.4%
K9me1K14me1K27me2 6% ± 3.6% K9me2K23acK27me3 5% ± 1.1% K9me2K27me3K36me1 5% ± 1.2%
K9me2K23acK27me3 5% ± 0.2% K9me2K27me3K36me1 5% ± 0.5% K9me2K36me3 5% ± 2.5%
K9me2K27me3K36me1 5% ± 0.9% K9me1K14me1K27me2 4% ± 0.8% K9me1K14me1K27me2 4% ± 2.9%
K9me2K23acK27me1K36me1 5% ± 1.8% K9me2K23acK27me1K36me1 3% ± 0.4% K9me1K14me1K27me2K36me2 4% ± 0.9%
K9me2K27me1K36me1 5% ± 1.2% K9me2K27me1K36me1 3% ± 1.7% K9me2K27me1K36me1 3% ± 2.3%
K9me2K36me3 3% ± 0.1% K9me3K27me2K36me2 3% ± 0.8% K9me2S10phK23me1K27me1 3% ± 2.3%
K9me1K14me1K27me2K36me2 3% ± 1.7% K9me2K36me3 3% ± 0.6% K9me2K27me1K36me3 3% ± 0.7%
K9me1K14me1K27me3 2% ± 1.1% K9me1K14me1K27me3 2% ± 0.5% K9me2S10phR26me2 2% ± 1.3%
K9me2K27me1K36me3 2% ± 0.4% K9me2K27me1K36me3 2% ± 0.8% K9me2S10phK27me3 2% ± 1.3%
K9me2K18acK27me3 2% ± 0.7% K27me3 2% ± 0.4% K27me3 2% ± 1.9%
K27me3 2% ± 0.8% K9me1K14me1K23acK27me2 2% ± 0.4% K9me2S10phK27me1K36me1 2% ± 2.6%
K9me1K14me1K23acK27me2 2% ± 0.4% K9me2K18acK27me3 2% ± 0.4% K9me1K14me1K23acK27me2 2% ± 0.9%
K9me2K23acK27ac 1% ± 0.2% K9me1K14me1K27me2K36me2 2% ± 0.4% K9me2K23acK27me1K36me1 2% ± 1.1%
K9me3K27me2K36me2 1% ± 0.3% K14me2K27me3 1% ± 1.2% K9me3S10phK27me2 2% ± 0.6%