Table 2.
Relative abundance for selected binary marks containing K9 methylation (average ± standard deviation of three replicates). Binary marks listed here were quantified in all LC-MS/MS analysis.
| Binary mark | H3.1_Asy | H3.1_G1 | H3.1_S | H3.1_M | H3.2_Asy | H3.2_G1 | H3.2_S | H3.2_M |
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| K9me1_K14me1 | 14% ± 4.8% | 12% ± 1.2% | 12% ± 5.3% | 13% ± 3.3% | 24% ± 2.0% | 16% ± 1.2% | 15% ± 0.5% | 15% ± 2.8% |
| K9me1_K18ac | 6% ± 1.2% | 2% ± 0.6% | 3% ± 0.3% | 1% ± 1.7% | 4% ± 1.5% | 1% ± 0.4% | 3% ± 0.4% | 2% ± 0.9% |
| K9me1_K23ac | 5% ± 0.3% | 5% ± 0.8% | 4% ± 1.7% | 5% ± 4.4% | 5% ± 0.9% | 3% ± 0.4% | 5% ± 0.9% | 2% ± 1.1% |
| K9me1_K27me2 | 15% ± 4.1% | 11% ± 1.7% | 11% ± 3.7% | 14% ± 3.5% | 23% ± 3.2% | 13% ± 3.0% | 12% ± 1.7% | 17% ± 3.4% |
| K9me1_K36me2 | 5% ± 2.6% | 5% ± 1.0% | 6% ± 2.3% | 2% ± 0.2% | 6% ± 0.5% | 5% ± 1.9% | 6% ± 0.3% | 7% ± 0.7% |
| K9me2_K14ac | 9% ± 1.9% | 3% ± 0.5% | 5% ± 1.1% | 1% ± 1.0% | 6% ± 0.9% | 2% ± 0.3% | 4% ± 0.3% | 4% ± 1.3% |
| K9me2_K18ac | 9% ± 2.4% | 7% ± 1.3% | 9% ± 1.1% | 3% ± 0.3% | 5% ± 1.4% | 5% ± 0.8% | 7% ± 0.2% | 1% ± 0.2% |
| K9me2_K23me1 | 3% ± 1.7% | 1% ± 0.7% | 1% ± 0.5% | 11% ± 1.2% | 2% ± 0.6% | 2% ± 0.8% | 2% ± 1.5% | 5% ± 2.4% |
| K9me2_K23ac | 14% ± 0.7% | 14% ± 4.9% | 17% ± 2.1% | 8% ± 3.9% | 7% ± 2.9% | 15% ± 1.0% | 15% ± 1.0% | 4% ± 1.1% |
| K9me2_K27me1 | 18% ± 1.6% | 16% ± 1.4% | 13% ± 0.9% | 20% ± 2.7% | 12% ± 3.5% | 15% ± 3.0% | 13% ± 1.8% | 16% ± 3.2% |
| K9me2_K27me3 | 19% ± 4.0% | 45% ± 2.6% | 52% ± 5.4% | 22% ± 5.7% | 24% ± 2.0% | 45% ± 4.1% | 48% ± 3.2% | 26% ± 3.7% |
| K9me2_K27ac | 6% ± 1.9% | 1% ± 0.6% | 2% ± 0.6% | 9% ± 2.3% | 4% ± 0.9% | 4% ± 0.5% | 2% ± 0.3% | 1% ± 0.3% |
| K9me2_K36me1 | 21% ± 2.3% | 17% ± 3.0% | 16% ± 3.3% | 16% ± 2.8% | 14% ± 4.6% | 19% ± 3.5% | 15% ± 2.5% | 15% ± 2.5% |
| K9me2_K36me3 | 4% ± 1.7% | 7% ± 2.1% | 6% ± 1.8% | 3% ± 1.1% | 3% ± 0.9% | 6% ± 0.9% | 7% ± 1.3% | 8% ± 2.4% |