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. 2021 Aug 17;15:3581–3591. doi: 10.2147/DDDT.S305378

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© 2021 Bian et al.

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Quantitative analysis of histological differences after gene therapy in four groups. The thicknesses of the combined IS and OS, ONL were measured every 400 µm across both the superior (S1-3) and inferior hemispheres (I1-3).(A) (3 months)/ (B) (6 months): quantification of the thickness of OS+IS of the retina from four groups. (C) (3 months)/ (D) (6 months): quantification of the thickness of ONL of the retina from four groups. Results were presented as median (min - max). n=8–12 per group. *P <0.05; **P <0.01 vs Rdh12^+/+-LD group. ^#P < 0.05 vs Rdh12^−/−-LD group. ^ΔP < 0.05 vs preventive group.