Table 3.
Stability of [18F]AlF-FAPI-74 for each formulation solution
Formulation solution | Elapsed time after synthesis (hr) | ||||
---|---|---|---|---|---|
Batch | 0 (EOS) | 2 | 3 | 4 | |
Radiochemical purity (%) | |||||
Saline | |||||
No. 1 | 98 | 96 | 79 | 54 | |
No. 2 | 97 | 96 | 94 | 89 | |
Saline containing 10 mg ascorbic acid and 90 mg sodium ascorbate (pH 5.0) | 98 | 97 | 96 | 95 | |
Saline containing 100 mg sodium ascorbate | 98 | 97 | 97 | 96 | |
Commercially available phosphate buffered saline (pH 7.4) | 98 | 96 | 96 | 95 | |
10 mM phosphate buffered saline (pH 6.7) | 98 | 96 | 95 | 89 | |
Commercially available phosphate buffered saline (pH 7.4) containing 100 mg sodium ascorbate | 98 | 97 | 97 | 97 | |
10 mM phosphate buffered saline (pH 6.7) containing 100 mg sodium ascorbate | |||||
No. 1 | 98 | 97 | 97 | 97 | |
No. 2 | 98 | 97 | 97 | 97 | |
No. 3 | 98 | 97 | 97 | 97 |
EOS, end of synthesis