Table 1.
Robustness study | Delineation (3 methods) | Attenuation correction | Motion | ||
---|---|---|---|---|---|
CT based | MR based | Average | Gating | ||
Number of patients | 9 | 9 | 10 | ||
Scanner manufacturer | GE Healthcare, Waukesha | GE Healthcare, Waukesha | GE Healthcare, Waukesha | GE Healthcare, Waukesha | |
Scanner model | Discovery 690 | Discovery 690 | SIGNA PET/MR | SIGNA PET/MR | SIGNA PET/MR |
Reconstruction method | VPFXS | VPFXS | VPFXS | VPFXS | VPFXS |
Attenuation correction | MR based: LAVA-flex pulse sequence | CT based | MR based: LAVA-Flex pulse sequence | MR based: LAVA-Flex pulse sequence | |
Time delay between FDG injection and PET scan start (min) | 71.5–92.5 | 71.5–92.5 | 40.3–117.6 | 57.1–75.9 | 36.8–82.0 |
Injected activity (MBq) | 181.2–252.3 | 181.2–252.3 | 136.2–259.3 | ||
Acquisition type | 3D | 3D | 3D | 4D (phase-gated) | |
Time per bed position (min) | 2 | 2 | 2 | 2 | 2 |
Resolution (mm) | 2.73 × 2.73 × 3.27 | 2.73 × 2.73 × 3.27 | 2.34 × 2.34 × 2.78 | 2.34 × 2.34 × 2.78 | 2.34 × 2.34 × 2.78 |
Delineation | Gradient-based threshold-based manual | Gradient based | Gradient based | Gradient based | Gradient based |
Intraclass correlation coefficient (ICC) | ICC(1,1) | ICC(3,1) | ICC(3,2) |
PET image dataset acquisition characteristics including reconstruction and delineation protocols for the three datasets are listed