Fig. 1. Upregulation of USP14 predicts poor clinical outcome in patients with HCC.
A The protein expression of USP14 in HCC tissues were examined by western blot. N stands for the adjacent non-tumorous tissues, T stands for HCC tissues. B The representative images and the statistical analysis were indicated. C, D The expression of USP14 in adjacent non-tumorous tissues, HCC tissues with different levels of differentiation was detected by IHC. Scale bar, 100 μM. E The representative images and the IHC scores were shown. F The clinical significance of USP14 expression in overall survival was evaluated in the TMA-based cohort by Kaplan–Meier survival analyses.
