Table. 2.

The segmented regression analysis results of the level and trend changes of the monthly proportion of patients who initiated medication with the study medicines before and after September 2017

Constant 95 %CI(lower, upper)	p-value	γ1 195 %CI(lower, upper)	p-value	γ2 295 %CI(lower, upper)	p-value	γ3 395 %CI(lower, upper)	p-value
0.22(0.15,0.31)	< 0.01	0.092(0.04,0.17)	0.08	0.183(0.104,0.34)	0.01	1.48(1.03,3.60)	0.02

Notes:

γ1indicates the slope of the trend of the monthly proportion of the patients who initiated medication with the study medicines before September 2017;

γ2 indicates the level change of the monthly proportion of the patients who initiated medication with the study medicines within the month of September 2017;

γ3 indicates the slope of the trend of the monthly proportion of patients who initiated medication with the study medicines after September 2017