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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Neuropsychology. 2021 May 20;35(5):472–485. doi: 10.1037/neu0000747

Table 4a.

Classification Statistics: TOMM Trial 1 Performance for Single and Two-variable Models Predicting Simulator (SIM) and Healthy Comparison (HC) Group Membership.

SnSp90 Youden
J
PPP
BR 40%
NPP
BR 40%
PPP
BR 10%
NPP
BR 10%
AUC AUC
95% CI
Χ2 Predictor
p
One-Variable Models:
Trial 1 Accuracy .67 0.64 .80 .85 .39 .97 .90 [.84, .96] 74.28***
Effort-Max .33−.35 0.25 .59 .69 .21 .93 .67 [.57, .77] 13.29***
View-Familiar (Max) .31 0.24 .58 .69 .19 .93 .66 [.56, .76] 11.40**
View-Unfamiliar (Max) .33 0.24 .58 .69 .19 .93 .66 [.56, .76] 12.33***
Response-Familiar (Max) .33−.35 0.24 .58 .69 .20 .92 .66 [.56, .76] 12.81***
Response-Unfamiliar (Max) .32−.34 0.24 .53 .71 .15 .94 .64 [.53, .75] 8.56**
Effort-Baseline .17 0.04 .46 .61 .17 .90 .55 [.45, .65] 2.12
View-Familiar (Baseline) .14−.15 0.05 .47 .61 .12 .90 .59 [.49, .69] 4.37*
View-Unfamiliar (Baseline) .15 0.04 .44 .61 .13 .91 .58 [.48, .69] 3.74
Response-Familiar (Baseline) .15−.17 0.04 .46 .61 .17 .90 .54 [.44, .65] 1.86
Response-Unfamiliar (Baseline) .12 0.08 .45 .63 .13 .90 .58 [.47, .70] 3.25
Effort-Range .54 0.45 .74 .76 .33 .95 .77 [.68, .86] 34.37***
Familiarity-Difference .19−.21 0.16 .55 .65 .16 .92 .66 [.56, .76] 7.50**

Two-Variable Models: Accuracy +
Effort-Max .76−.82 0.68 .84 .86 .45 .97 .94 [.90, .98] 90.76*** .011
View-Familiar (Max) .76−.80 0.66 .84 .85 .45 .97 .94 [.90, .98] 90.49*** .012
View-Unfamiliar (Max) .76−.82 0.66 .84 .85 .45 .97 .94 [.90, .98] 90.90*** .010
Response-Familiar (Max) .76−.82 0.68 .84 .86 .45 .97 .94 [.90, .98] 90.90*** .010
Response-Unfamiliar (Max) .66−.76 0.63 .79 .84 .40 .98 .92 [.87, .97] 72.19*** .016
View-Familiar (Baseline) .76−.78 0.66 .84 .85 .45 .97 .94 [.90, .98] 88.14*** .027
Effort-Range .71−.75 0.62 .80 .84 .39 .97 .93 [.89, .97] 83.76*** .023
Familiarity-Difference .69−.83 0.69 .84 .87 .48 .97 .90 [.84, .96] 77.49*** .081

Note. SnSp90 = Sensitivity (detection of simulated TBI) when Sp Specificity (bona fide TBI) is set at cut point ≥ .90 (range presented when cut point is associated with multiple Sn values); PPP = Positive Predictive Power, NPP = Negative Predictive Power (each presented for 40% and 10% base rate); AUC = ROC area under the curve. See Table 1 for pupil variable abbreviation key.