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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Neuropsychology. 2021 May 20;35(5):472–485. doi: 10.1037/neu0000747

Table 4b.

Classification Statistics: TOMM Trial 2 Performance for Single and Two-variable Models Predicting Simulator (SIM) and Healthy Comparison (HC) Group Membership.

SnSp90 Youden
J		 PPP
BR 40%		 NPP
BR 40%		 PPP
BR 10%		 NPP
BR 10%		 AUC AUC
95% CI		 Χ2 Predictor
p
One-Variable Models:
Trial 2 Accuracy .84 0.71 .93 .85 .69 .97 .89 [.82, .96] 82.65***
Effort-Max .33 0.28 .66 .69 .23 .93 .68 [.58, .78] 12.02**
View-Familiar (Max) .29 0.16 .58 .65 .19 .92 .66 [.56, .76] 9.69**
View-Unfamiliar (Max) .29 0.20 .61 .66 .19 .92 .66 [.56, .76] 10.07**
Response-Familiar (Max) .33 0.26 .65 .68 .24 .93 .67 [.57, .77] 10.26**
Response-Unfamiliar (Max) .37 0.07 .42 .80 .11 1.00 .71 [.58, .85] 6.58*
Effort-Baseline .16−.18 0.04 .57 .61 .20 .91 .54 [.44, .65] 1.28
View-Familiar (Baseline) .16 0.04 .50 .61 .10 .90 .58 [.48, .68] 2.75
View-Unfamiliar (Baseline) .16 0.03 .50 .61 .11 .90 .57 [.47, .67] 2.43
Response-Familiar (Baseline) .16−.18 0.04 .57 .61 .20 .91 .54 [.44, .64] 1.08
Response-Unfamiliar (Baseline) .26 0.06 .41 1.00 .11 1.00 .60 [.44, .76] 2.62
Effort-Range .55 0.44 .77 .75 .37 .94 .78 [.70, .86] 38.34***
Familiarity-Difference .24 0.12 .61 .63 .21 .91 .61 [.51, .71] 4.65*
Two-Variable Models: Accuracy +
Effort-Max .82−.84 0.70 .95 .85 .75 .97 .90 [.83, .96] 83.96*** .258
View-Familiar (Max) .82−.84 0.70 .95 .85 .75 .97 .90 [.83, .96] 83.88*** .272
View-Unfamiliar (Max) .82−.84 0.70 .95 .85 .75 .97 .90 [.83, .96] 83.92*** .265
Response-Familiar (Max) .82 0.70 .95 .85 .75 .97 .90 [.83, .96] 84.02*** .247
Response-Unfamiliar (Max) .79 0.72 .83 .89 .45 .98 .95 [.89, 1.00] 37.01*** .351
Effort-Range .82 0.67 .90 .84 .56 .97 .92 [.86, .97] 86.52*** .053
Familiarity-Difference .82 0.71 .93 .85 .69 .97 .89 [.82, .96] 87.72*** .783

Note. SnSp90 = Sensitivity (detection of simulated TBI) when Sp Specificity (bona fide TBI) is set at cut point ≥ .90 (range presented when cut point is associated with multiple Sn values); PPP = Positive Predictive Power, NPP = Negative Predictive Power (each presented for 40% and 10% base rate); AUC = ROC area under the curve. See Table 1 for pupil variable abbreviation key.