Table 1.
Subject anthropomorphic and clinical data.
| . | Obese | Morbidly obese | p value |
|---|---|---|---|
| Age |
44 (12.6) n = 8 |
42 (7.7) n = 8 |
0.655 |
| Sex |
2M/6F n = 8 |
2M/6F n = 8 |
N/A |
| Race |
1B/7C n = 8 |
3B/5C n = 8 |
N/A |
| Height (in) |
64.8 (4.4) n = 8 |
66.1 (4.7) n = 8 |
0.553 |
| Weight (Lbs) |
232.8 (36.9) n = 8 |
411.8 (41.4) n = 8 |
<0.0001** |
| BMI (Kg/m2) |
38.8 (1.1) n = 8 |
66.6 (7.9) n = 8 |
<0.0001** |
| Hypertension |
5Y/3N n = 8 |
5Y/3N n = 8 |
N/A |
| Beta-Blockers |
1Y/7N n = 8 |
0Y/8N n = 8 |
N/A |
| Diabetes |
0Y/8N n = 8 |
0Y/8N n = 8 |
N/A |
| A1C (%) |
5.7 (0.5) n = 5 |
5.5 (0.3) n = 5 |
0.538 |
|
Fasting Glucose (mg/dL) |
108 (35.5) n = 8 |
111 (35.8) n = 8 |
0.889 |
|
Fasting Insulin (µIU/ml) |
11.4 (8.3) n = 8 |
20.5 (25.9) n = 6 |
0.365 |
| HOMA-B (%) |
88 (49.6) n = 7 |
148 (145.3) n = 6 |
0.325 |
| HOMA-IR |
3.5 (3.7) n = 8 |
6.6 (9.3) n = 6 |
0.405 |
| QUICKI |
0.15 (0.02) n = 8 |
0.14 (0.02) n = 6 |
0.514 |
| Adiponectin (ng/ml) |
6808 (2786) n = 8 |
4222 (719) n = 4 |
0.104 |
| MCP1 (pg/ml) |
220 (117) n = 8 |
226 (183) n = 4 |
0.944 |
| Creatinine (mg/dL) |
0.875 (0.10) n = 8 |
0.888 (0.16) n = 8 |
0.858 |
| AST (U/L) |
26 (7.5) n = 8 |
35 (33.5) n = 7 |
0.483 |
| ALT (U/L) |
34 (25.8) n = 8 |
43 (37.1) n = 8 |
0.603 |
Mean and standard deviation (SD) values for anthropomorphic variables, plasma clinical measures and calculated surrogate measures of insulin sensitivity.
**indicate statistically significant differences at p-value < 0.01.