Table 3.
Comparison of clinical and laboratory features between SLE patients with and without neutropenia
| Variables | With neutropenia (n = 26) | Without neutropenia (n = 99) | p |
|---|---|---|---|
| Age (years), median (range) | 42.4 ± 17.3 | 39.0 ± 14.9 | 0.368 |
| Female | 25 (96.2) | 91 (91.9) | 0.684 |
| Disease duration (months), median (range) | 18.0 (0.2–324.0) | 24.0 (0.1–360.0) | 0.434 |
| Treated patients | 10 (38.5) | 66 (66.7) | 0.009 |
| C3 (g/l), mean ± SD | 0.390 (0.060–0.960) | 0.530 (0.200–1.120) | 0.004 |
| Leukopenia | 26 (100.0) | 24 (24.2) | < 0.001 |
| Leukocyte count (109/l), median (range) | 2.3 (1.3–3.4) | 4.6 (2.4–12.5) | < 0.001 |
| Lymphopenia | 20 (76.9) | 49 (49.5) | 0.012 |
| Lymphocyte count (109/l), median (range) | 0.7 (0.3–1.4) | 1.1 (0.2–3.6) | 0.001 |
| Thrombocytopenia | 18 (69.2) | 23 (23.2) | < 0.001 |
| Platelet count (109/l), mean ± SD | 116.3 ± 73.3 | 181.1 ± 91.0 | 0.001 |
| Cylindruria | 6 (23.1) | 6 (6.1) | 0.009 |
Except where indicated otherwise, values are n (%)
C3 complement 3, SLE systemic lupus erythematosus