Table 3.
Univariate and multivariate linear regression models with 25(OH) vitamin D as the dependent variable
Predictors | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
Coefficient | P value | Coefficient | P value | |
Age at TDM | − 0.959 | < 0.001*** | − 0.934 | < 0.001*** |
Sex | ||||
Female | Reference | Reference | ||
Male | 5.958 | < 0.001*** | 4.370 | < 0.001*** |
Season | ||||
Spring | 0.379 | 0.785 | − 0.219 | 0.859 |
Summer | 4.213 | < 0.001*** | 3.162 | 0.002** |
Autumn | 3.497 | 0.010* | 2.632 | 0.030* |
Winter | Reference | Reference | ||
MPA AUC0–24h | 0.040 | < 0.001*** | 0.034 | < 0.001*** |
Glucocorticoid daily dose | − 0.094 | < 0.001*** | − 0.101 | < 0.001*** |
Vitamin D3 supplements |
4.834 | 0.002** | 4.946 | < 0.001*** |
Vitamin D receptor activators | − 2.768 | 0.003** | − 1.089 | 0.206 |
TDM therapeutic drug monitoring, MPA mycophenolic acid, AUC0–24h area under the MPA concentration–time curve over 24 h
***P < 0.001, **P < 0.01, *P < 0.05