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. 2021 Jun 17;8(3):1143–1157. doi: 10.1007/s40744-021-00324-w

Table 3.

Univariate and multivariate linear regression models with 25(OH) vitamin D as the dependent variable

Predictors Univariate analysis Multivariate analysis
Coefficient P value Coefficient P value
Age at TDM − 0.959 < 0.001*** − 0.934 < 0.001***
Sex
 Female Reference Reference
 Male 5.958 < 0.001*** 4.370 < 0.001***
Season
 Spring 0.379 0.785 − 0.219 0.859
 Summer 4.213 < 0.001*** 3.162 0.002**
 Autumn 3.497 0.010* 2.632 0.030*
 Winter Reference Reference
MPA AUC0–24h 0.040 < 0.001*** 0.034 < 0.001***
Glucocorticoid daily dose − 0.094 < 0.001*** − 0.101 < 0.001***

Vitamin D3

supplements

4.834 0.002** 4.946 < 0.001***
Vitamin D receptor activators − 2.768 0.003** − 1.089 0.206

TDM therapeutic drug monitoring, MPA mycophenolic acid, AUC0–24h area under the MPA concentration–time curve over 24 h

***P < 0.001, **P < 0.01, *P < 0.05