Table 4.

Stratification by centre

	Brest	Angers/Le Mans	Poitiers	Rennes	Tours	p value
Number	9	7	4	19	7
1st biotherapy efficiency	6/9 (66.7)	2/6 (33.3)	4/4 (100.0)	17/19 (89.5)	4/7 (57.1)	0.055
1st biotherapy duration (days)	61.0 (26.0–92.0)	214.0 (77.0–700.0)	443.0 (216.0–1140.8)	363.0 (120.5–699.5)	3.0 (3.0–24.0)	0.057
Reason for introduction
Crisis	5 (55.6)	0 (0.0)	1 (25.0)	0 (0.0)	5 (71.4)	< 0.001
Crisis/long term	0 (0.0)	1 (14.3)	0 (0.0)	11 (57.9)	0 (0.0)
Long-term	4 (44.4)	6 (85.7)	3 (75.0)	8 (42.1)	2 (28.6)

Data are presented as n (%) or median (Q1–Q3)