Published literature on patient-reported outcome measures (PROMs) in patients with Takayasu arteritis (TAK) is sparse.

Available evidence appears to suggest that patients with TAK have greater disability and depression than healthy individuals and that active TAK is associated with worse quality of life, disability, depression and anxiety.

However, the comparison of PROMs from patients with TAK and healthy controls and from those with active and those with inactive disease is based on small numbers of studies with considerable statistical heterogeneity in some of the pooled estimates (therefore, requiring cautious interpretation).

Research gaps in this area include the assessment of longitudinal changes in PROMs in patients with TAK, changes following therapy and relationship of PROMs with disease activity.

There is a need to develop a validated disease-specific PROM for patients with TAK.