TABLE 5.
Percent change in markers of inflammation by quintiles of kitchen area BC and NO2 in multi-pollutant model in subsample of 92 participantsa
| TNF-α (n = 92) |
IL-1β (n = 92) |
IL-10 (n = 92) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Change (%) | 95 % | CI | p-value | Change (%) | 95 % | CI | p-value | Change (%) | 95 % | CI | p-value |
| Kitchen NO2 | |||||||||||
| Reference | |||||||||||
| 0 | −25 | 34 | 0.997 | −58 | −77 | −23 | 0.006 | 15 | −13 | 51 | 0.318 |
| 6 | −23 | 47 | 0.709 | −33 | −66 | 31 | 0.233 | 5 | −23 | 42 | 0.768 |
| −7 | −38 | 39 | 0.719 | −70 | −87 | −31 | 0.005 | 8 | −26 | 58 | 0.669 |
| 0 | −33 | 49 | 0.985 | −58 | −82 | −3 | 0.043 | 35 | −7 | 96 | 0.113 |
| Linear trend significanceb | 0.737 | 0.347 | 0.678 | ||||||||
| Kitchen BC | |||||||||||
| Reference | |||||||||||
| 7 | −23 | 47 | 0.687 | 74 | −11 | 239 | 0.105 | −28 | −46 | −2 | 0.036 |
| −8 | −38 | 34 | 0.648 | −16 | −62 | 86 | 0.660 | −43 | −60 | −18 | 0.003 |
| 33 | −12 | 99 | 0.172 | −15 | −63 | 99 | 0.709 | −35 | −55 | −5 | 0.028 |
| 42 | −8 | 120 | 0.113 | 6 | −57 | 161 | 0.905 | −35 | −57 | −2 | 0.041 |
| Linear trend significanceb | 0.140 | 0.221 | 0.030 | ||||||||
Abbreviations: BC, black carbon; BMI, body mass index; CI, confidence interval; CO, carbon monoxide; IL-10, anti-inflammation marker; NO2, nitrogen dioxide; PM2.5, fine particulate matter; TNF-α and IL-1β, markers associated with a pro-inflammatory response.
Each marker of inflammation model includes the following covariates: age, BMI, wealth quintile, season, type of fuel (use of wood and dung vs. only dung), and quintiles of BC, NO2, PM2.5, and CO.
p-values of linear trends were obtained using t tests on log-transformed continuous pollutant concentrations.