Table 2.
Phthalate metabolite concentrations in MWHS and NHANES.
| Name | Abbreviation | MWHS (2006–2015) n=718 | NHANES (2005–2016) n=7571 |
|---|---|---|---|
| Phthalate metabolitev | Median (25th, 75th percentile) in ng/mL | ||
| Mono(2-ethylhexyl) phthalate | MEHP | 4.5 (2.7, 9.4) | 1.2 (0.6, 3.1) |
| Mono(2-ethyl-5-hydroxyhexyl) phthalate | MEHHP | 33.7 (20.3, 58.1) | 9.1 (3.4, 22.5) |
| Mono(2-ethyl-5-oxohexyl) phthalate | MEOHP | 12 (7.3, 22.3) | 5.6 (2.1, 13.2) |
| Mono(2-ethyl-5-carboxypentyl) phthalate | MECPP | 25.8 (15.8, 48.1) | 13.4 (5.6, 31.7) |
| Mono(3-carboxypropyl) phthalate | MCPP | 2.5 (1.3, 5.4) | 1.4 (0.6, 3.4) |
| Monobenzyl phthalate | MBzP | 9.4 (5.4, 16) | 4.1 (1.8, 10.4) |
| Monoethyl phthalate | MEP | 95.4 (47.4, 192) | 58.8 (20.0, 179.6) |
| Mono-n-butyl phthalate | MBP | 19.7 (12.9, 32.6) | 11.5 (5.4, 25.3) |
| Mono-isobutyl phthalate | MiBP | 16.3 (9.8, 26.1) | 5.7 (2.6, 13.1) |
| Phthalate molar-converted sum | Median (25 th , 75 th percentile) in nmol/mL | ||
| Sum of di(2-ethylhexyl) phthalate metabolites | ∑DEHP2 | 0.3 (0.2, 0.5) | 0.1 (0.04, 0.2) |
| Sum of all plastic phthalate metabolites | ∑Plastics3 | 0.3 (0.2, 0.6) | 0.1 (0.1, 0.3) |
| Sum of all personal care product phthalate metabolites | ∑PCP4 | 0.7 (0.4, 1.3) | 0.4 (0.2, 1.2) |
| Sum of all phthalate metabolites | ∑Phthalates5 | 1.1 (0.7, 2) | 0.7 (0.3, 1.8) |
| Sum of anti-androgenic phthalate metabolites | ∑AA6 | 0.5 (0.3, 0.8) | 0.2 (0.1, 0.5) |
1
Weighted phthalate concentrations for 45–54 year-old US women from combined NHANES cycles 2005–06, 2007–08, 2009–10, 2011–12, 2013–14, and 2015–16. MWHS, Midlife Women’s Health Study; NHANES, National Health and Nutrition Examination Survey.
2
∑DEHP: MEHP, MEHHP, MEOHP, MECPP.
3
∑PCP: MEP, MBP, and MiBP.
4
∑Plastics): MCPP, MBzP, MEHP, MEHHP, MEOHP, MECPP.
5
∑Phthalates: all phthalate metabolites.
6
∑AA: MBzP, MEHP, MEHHP, MEOHP, MECPP, MBP, MiBP.