HFD-induced alterations in food preference are reversed by exercise. (A) Schematic illustrating the experimental setup. (B) Preference for the more energy dense test chow during the food preference test. Two-way ANOVA with Bonferroni post-hoc comparison; n=8–14/group; Fexercise(1,35)=7.401, p=0.0101; Fdiet(1,35)=11.01, p=0.0021. (C) Total amount of both test chows consumed during the food preference test corrected for body weight. Two-way ANOVA with Bonferroni post-hoc comparison; n=8–14/group; Fexercise(1,35)=1.516, p=0.2264; Fdiet(1,35)=68.63, p<0.0001. Data are represented as mean ± SEM. **p < 0.01; ***p < 0.001; ****p < 0.0001. See also Supplemental Figure 5.