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. 2021 Aug 9;8:689313. doi: 10.3389/fcvm.2021.689313

Table 1.

Classification on myopathy, called by the acronym EHRA.

EHRAs Histology Clinical correlation
I Hypertrophy and myocytolysis of cardiomyocytes. Absence of fibrosis or interstitial changes Isolated AF, genetic disease, diabetes mellitus
II Predominance of fibrosis (collagen deposition). Normal cardiomyocytes Elderly and smoking
III Mixture of classifications I and II Heart failure and valvulopathies
IV Alteration of the interstitial matrix with no collagen accumulation. Accumulation examples: amyloid, fat, inflammatory cells, among others Amyloidosis, inflammatory diseases, granulomatosis, among others