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. 2021 Aug 9;12:710121. doi: 10.3389/fimmu.2021.710121

Figure 1.

Figure 1

T-cell recruitment via PSGL-1/selectin binding. In the blood vessel, the circulating T-cell is engaged by selectin on platelets (P-selectin) or endothelial cells (P-selectin or E-selectin). Subsequently, the T-cell is able to initiate rolling and the extravasation cascade, leading to its recruitment into the site of inflammation, where it can intervene as an effector cell. This process can also take place in the recruitment of other leukocytes.