Association of early treatment with azathioprine with the need for surgical procedures before and after 2009
Before 2009, patients with early azathioprine treatment had a lower risk of surgery (12.3% versus 19.1%, p = 0.041). This effect is no longer present after 2009, with fewer operations and a higher proportion of patients with early administration of azathioprine and other interventions (including early administration of infliximab).