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. 2021 Aug 9;12:703894. doi: 10.3389/fphar.2021.703894

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Copyright © 2021 Lai, Lin, Wu, Tsai and Tsai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of CA on _L-dopa-induced abnormal involuntary movements (AIMs) in 6-OHDA lesioned rats. The axial, limb, and orofacial AIMs were calculated on days 12, 26, and 33 for 1 min every 20 min over 120 min. (A) The integrated AIM scores of axial, limb, and orofacial subtype on day 26 over 120 min. (B) The ALO score (the sum of axial, limb, and orofacial) on day 26 for 1 min every 20 min over 120 min. (C) The ALO score on days 12, 26, and 33. The results are expressed as mean ± SEM (n = 5). Means without a common letter differ, p < 0.05.