Table 2.

Numbers contributed to each subtype analysis, by study

	Noncancers	Cancers
		All	Family history			Metastatic			Gleason				Aggressive				Age at diagnosis			Death
			FH+	FH–	U	M1	M0	U	>7	7	<7	U	Agg.	Int.	Non.	U	<65	≥65	U	PrCa
Tier 1 status
+ve	8	65	26	27	12	8	43	14	18	14	21	12	35	11	15	4	50	14	1	21
–ve	3345	5495	2053	2557	885	496	3885	1114	1283	1350	2102	760	2202	1178	1652	463	3660	1714	121	1182
+ve Prev (%)	(0.24)	(1.17)	(1.25)	(1.04)		(1.59)	(1.09)		(1.38)	(1.03)	(0.99)		(1.56)	(0.93)	(0.90)		(1.35)	(0.81)		(1.75)
Total	3353	5560	2079	2584	897	504	3928	1128	1301	1364	2123	772	2237	1189	1667	467	3710	1728	122	1203
Tier 2 status
+ve	135	387	153	169	65	35	272	80	81	106	153	47	143	99	120	25	265	117	5	69
–ve	3218	5173	1926	2415	832	469	3656	1048	1220	1258	1970	725	2094	1090	1547	442	3445	1611	117	1134
+ve Prev (%)	(4.03)	(6.96)	(7.36)	(6.54)		(6.94)	(6.92)		(6.23)	(7.77)	(7.21)		(6.39)	(8.33)	(7.20)		(7.14)	(6.77)		(5.74)
Total	3353	5560	2079	2584	897	504	3928	1128	1301	1364	2123	772	2237	1189	1667	467	3710	1728	122	1203
Tier 1 + 2 status
+ve	143	448	178	193	77	43	312	93	99	120	171	58	176	109	134	29	312	130	6	88
–ve	3210	5112	1901	2391	820	461	3616	1035	1202	1244	1952	714	2061	1080	1533	438	3398	1598	116	1115
+ve Prev (%)	(4.26)	(8.06)	(8.56)	(7.47)		(8.53)	(7.94)		(7.61)	(8.80)	(8.05)		(7.87)	(9.17)	(8.04)		(8.41)	(7.52)		(7.32)
Total	3353	5560	2079	2584	897	504	3928	1128	1301	1364	2123	772	2237	1189	1667	467	3710	1728	122	1203

Agg. = aggressive; FH = family history; Int. = intermediate aggressive; Non. = nonaggressive; PrCa = prostate cancer; Prev = prevalence; U = unknown.