Table 4.

Multivariate analyses of prognostic factors correlated with OS and CSS with regard to B7 score

Variables	OS				CSS
	Training cohort		Validation cohort		Training cohort		Validation cohort
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Gleason score 7 (4+3)−10/6–7 (3+4)	1.46	0.37	3.64	0.043	1.24	0.682	3.15	0.147
	0.64 to 3.37		1.04 to 12.73		0.45 to 3.41		0.67 to 14.87
Tumor stage	1.04	0.927	3.11	0.021	1.1	0.845	2.93	0.086
T3–4/T2	0.47 to 2.28		1.19 to 8.12		0.42 to 2.87		0.86 to 10.03
Nodal metastasis	2.66	0.023	2.55	0.243	3.3	0.019	2.69	0.233
Present/Absent	1.15 to 6.19		0.53 to 12.30		1.21 to 8.98		0.53 to 13.73
Distal metastasis	5.43	<0.001	1.57	0.434	6.53	<0.001	2.57	0.146
Present/Absent	2.36 to 12.52		0.51 to 4.85		2.44 to 17.48		0.72 to 9.14
B7 score	4.33	0.018	10.76	0.022	4.54	0.046	6.52	0.077
High/Low	1.29 to 14.56		1.41 to 82.50		1.03 to 20.02		0.82 to 52.09

P values <0.05 marked in bold font are statistically significant.

CSS, cancer-specific survival; OS, overall survival.