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. 2021 Aug 9;11:713328. doi: 10.3389/fonc.2021.713328

Table 2.

Proportion of patients treated with radiotherapy increased over time for various breast cancer stages but for T1aN0 patients.

Stage 1988 to 1997 1998 to 2007 2008 to 2012 Relative change
DCIS 34.9% (N=3,163) 39.4% (N=6,159) 41.1% (N=1,793) + 17.8%
T1aN0 65.1% (N=8,654) 54.0% (N=21,346) 53.0% (N=14,372) - 18.6%
T1bN0 49.6% (N=23,010) 59.2% (N=58,503) 57.1% (N=34,269) + 15.1%
T1cN0 43.1% (N=40,785) 53.3% (N=100,921) 52.1% (N=58,396) + 21.0%
Stage IIA – T2 30.2% (N=22,204) 41.1% (N=55,816) 41.2% (N=36,798) + 36.4%
Stage IIA – N1 39.1% (N=13,718) 51.9% (N=41,282) 53.8% (N=21,761) + 37.6%
Stage IIB 31.0% (N=13,656) 45.9% (N=41,238) 50.2% (N=27,025) + 61.9%
Stage IIIA 39.5% (N=12,939) 61.9% (N=29,419) 64.5% (N=16,875) + 63.3%
Stage IIIB 44.7% (N=4,762) 50.0% (N=11,179) 53.0% (N=5,726) + 18,6%
Stage IIIC 45.3% (N=7,060) 61.6% (N=14,753) 62.3% (N=8,103) + 37.5%

The variations for each stage are statistically significant (p < .001).