Table 4.

Annual number and mortality of secondary lung secondary cancers for patients diagnosed in 2019 with early-stage breast cancers depending on the radiotherapy technique.

Radiotherapy technique	Dose (Gy) / Fractionation	Mean lung dose	Radiation induced lung cancers	Secondary lung cancer excess death	Percent risk reduction
Standard WBI	42.5/16	2.021 Gy	3,625	2,900	–
VMAT WBI	42.5/16	1.821 Gy	3,076	2,461	9.9%
FAST-Forward WBI	26/5	1.236 Gy	2,088	1,670	38.8%
Prone WBI	42.5/16	0.600 Gy	1,076	861	70.3%
3D-CRT APBI	38.5/10	1.146 Gy	1,936	1,549	43.3%
Shorter 3D-CRT APBI	26/5	0.774 Gy	1,307	1,046	61.7%
Multicatheter HDR APBI	34/10	0.584 Gy	986	789	71.1%
Seeds LDR APBI	90/1	0.39 Gy	659	527	80.7%
Robotic 4π APBI	28.5/5	0.30 Gy	507	406	85.2%