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. 2021 Aug 9;12:723145. doi: 10.3389/fphar.2021.723145

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Copyright © 2021 Yang, Shao, Wu, Pan, Yang, Pan and Jin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TRX promoted osteoblast differentiation of MSCs. (A) Qualitative examiation of ALP staining and ARS staining. (B) The quantitative assay of ALP activity. (C) The quantitative assay of ARS staining. (D) The quantitative assay of OD value. (E) The expression of several osteogenic marker genes was measured by qRT-PCR assays at day 14. *, p < 0.05; **, p < 0.01; ***, p < 0.001; vs. Control.