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. 2021 Aug 23;21:861. doi: 10.1186/s12879-021-06575-w

Table 3.

Diagnostic value of IL-33, ADA and peripheral blood T-SPOT.TB in pleural effusion for tuberculous pleurisy

Cut-off value Sensitivity (%) Specificity (%) AUC (95% CI)
IL-33 155.96 ng/l 49.1 100.0 0.753 (0.637–0.869)
ADA 30.55 U/l 93.0 90.9 0.912 (0.804–1.000)
T-SPOT.TB 25.35 pg/ml 92.3 71.4 0.865 (0.713–1.000)

AUC were 0.753, 0.912, 0.865 respectively for pleural IL-33, pleural ADA and peripheral blood T-SPOT. The sensitivities were 49.1%, 93%, 92.3% with specificity of 100%, 90.9%, 71.4% respectively using the cut-off value of 155.96 ng/l for IL-33, 30.55 U/l for ADA, 25.35 pg/ml for T-SPOT.TB respectively