Table 5.

The positive predictive value and negative predictive value of the indices, alone and in combinations

Test method			Gold standard
			Positive	Negative
IL-33	PPV 100.0%	Positive	28	0
	NPV 43.1%	Negative	29	22
ADA	PPV 96.4%	Positive	53	2
	NPV 83.3%	Negative	4	20
T-SPOT.TB	PPV 89.8%	Positive	53	6
	NPV 80.0%	Negative	4	16
IL-33 + ADA	PPV 94.6%	Positive	53	3
	NPV 82.6%	Negative	4	19
IL-33 + T-SPOT.TB	PPV 100.0%	Positive	44	0
	NPV 62.9%	Negative	13	22
ADA + T-SPOT.TB	PPV 100%	Positive	48	0
	NPV 71.0%	Negative	9	22
IL-33 + ADA + T-SPOT.TB	PPV 100.0%	Positive	50	0
	NPV 75.9%	Negative	7	22

The positive predictive value and negative value for IL-33, ADA, T-SPOT.TB were 100.0%, 43.1%; 96.4%, 83.3%; 89.8%, 80.0% respectively

PPV positive predictive value, NPV negative predictive value