Table 2.

Key direct targets of anlotinib combined with XHW in the treatment of lung cancer.

No.	Gene names	Protein names	UniProt ID
1	BCHE	Cholinesterase	P06276
2	ALOX5	Arachidonate 5-lipoxygenase	P09917
3	PTGS2	Prostaglandin G/H synthase 2	P35354
4	PTGS1	Prostaglandin G/H synthase 1	P23219
5	LPL	Lipoprotein lipase	P06858
6	CES1	Liver carboxylesterase 1	P23141
7	PPARG	Peroxisome proliferator-activated receptor gamma	P37231
8	PLA2G2E	Group IIE secretory phospholipase A2	Q9NZK7
9	PLA2G1B	Phospholipase A2	P04054
10	UGCG	Ceramide glucosyltransferase	Q16739
11	LCT	Lactase-phlorizin hydrolase	P09848
12	ADRA1A	Alpha-1A adrenergic receptor	P35348
13	ADRB1	Beta-1 adrenergic receptor	P08588
14	ADRB2	Beta-2 adrenergic receptor	P07550
15	MAOB	Amine oxidase [flavin-containing] B	P27338
16	ADRA2A	Alpha-2A adrenergic receptor	P08913
17	MAOA	Amine oxidase [flavin-containing] A	P21397
18	TAAR1	Trace amine-associated receptor 1	Q96RJ0
19	ADRA2B	Alpha-2B adrenergic receptor	P18089
20	GATM	Glycine amidinotransferase, mitochondrial	P50440
21	c-Kit	Mast/stem cell growth factor receptor Kit	P10721
22	FGFR4	Fibroblast growth factor receptor 4	P22455
23	EGFR	Epidermal growth factor receptor	P00533
24	CCL2	C-C motif chemokine 2	P13500
25	FGFR3	Fibroblast growth factor receptor 3	P22607
26	VEGFR2,	Vascular endothelial growth factor receptor 2	P35968
27	VEGFR1,	Vascular endothelial growth factor receptor 1	P17948
28	FGFR2	Fibroblast growth factor receptor 2	P21802
29	PDGFRB,	Platelet-derived growth factor receptor beta	P09619
30	FGFR1	Fibroblast growth factor receptor 1	P11362
31	PDGFRA	Platelet-derived growth factor receptor alpha	P16234
32	MKI67	Proliferation marker protein Ki-67	P46013
33	MET	Hepatocyte growth factor receptor	P08581
34	DDR1	Regulatory protein E2	P08345
35	MVD	Diphosphomevalonate decarboxylase	P53602
36	RET	Proto-oncogene tyrosine-protein kinase receptor Ret	P07949