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. 2021 Aug 23;26:100714. doi: 10.1016/j.imu.2021.100714

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 4 — Docking of α7 nAChR with HCQ: (a) Docked pose: α7 nAChR bound HCQ towards interface of two subunit at the orthosteric site (left – surface view, right – ribbon representation of protein); (b) Superimposed image view: nicotine (blue-docked ligand, yellow-crystal structure ligand) interacting with α7 nAChR protein in the same cleft as HCQ (within A, B, and C loop). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)