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TOP3β interaction with HCQ towards the site near to catalytic pocket (left – surface view, right – ribbon representation of protein) (Asp119, Asp 386) and important DNA/RNA binding regulatory regions (pink color marked region: catalytic residues) (Hydrogen bond –pink color line, salt bridge-blue, hydrophobic interaction –green). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
