Table 4.

HCQ docking studies with the protein targets using AutoDock Vina: score & interacting residues details.

PROTEIN TARGETS	AFFINITY (kcal/mol)	HYDROGEN BONDS	HYDROPHOBIC INTERACTING RESIDUES
ACE2	−6.2	Glu 208	Gln 102, Tyr 196, Gln 98, Leu 95, Pro 565, Asp 206, Ala 396
α7 nAChR	−6.2	Ser 77, Asp 87	Trp 145, Ile 80, Val 85, Tyr 116
α1D-AR	−6.4	Asp 80, Cys 150	Lys 289, Phe 288, Asp 80, Trp 76, Ala 77, Phe 292, Ser 283
TOP 3β	−6.1	Asp 185, Phe 214	Arg 181, Gly 189, Gln 182, Ala 512, Gln 218, Arg 524, His 517