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. 2021 Jul 6;246(16):1810–1815. doi: 10.1177/15353702211023846

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Figure 1. — Interaction between ADSCs and OC cells. ADSCs affect OC cells by secreting soluble factors or extracellular vesicles. OC cells influence ADSCs to differentiate into CAFs or CAAs which in turn promote OC progression, metastasis, and chemoresistance through multiple mechanisms. ADSC, adipose-derived stem cell; CAF, cancer-associate fibroblast; CAA, cancer-associate adipocyte; OC, ovarian cancer; EMT, epithelial-mesenchymal transition; ECM, extracellular matrix. (A color version of this figure is available in the online journal.)