TABLE 2.
Locus-level replication analysis of FOCAD × PRICKLE1 detected significantly interacting SNP pairs between one of the two SNPs (rs10964862 and rs10123324) at the FOCAD locus and different PRICKLE1 SNPs.
| FOCAD locus | PRICKLE1 locus Top interacting SNP | Interaction p | |||||||
|
|
|
||||||||
| SNP | Gene | Distance from rs10511683 (kb) | MAF | No. of significant interactions | SNP | Gene | Distance from rs1796391 (kb) | MAF | |
| rs10964862 | IFNW1 5′-UTR | 340 | 0.138 | 10 | rs11181736 | Intergenic | 380 | 0.124 | 4.53E-09 |
| rs10123324 | MLLT3 intron | 345 | 0.214 | 5 | rs10785368 | LINC02451 intron | 190 | 0.430 | 1.29E-06 |
SNP, single nucleotide polymorphism; MAF, minor allele frequency.