Figure 6.

Colonization of B. animalis reduced the polyp number in Apc^Min/+ mice. (a) The presence of B. animalis in the fecal samples from the inoculated Apc^Min/+ mice, detected by qPCR. (b) Total polyps count, and the size distribution of the polyps. Ten Apc^min/+ mice (aged 8 weeks, male) were randomly divided into B. animalis treatment group and control group. Five mice were gavage with 1 × 10⁹ CFU dose of B. animalis weekly for three consecutive weeks to the treatment group. Control group was fed with equal volume of water. Data is presented as the mean ± SD, n = 5. Statistically significance was calculated with two-way ANOVA multiple comparison for (a) and T-test for (b). *p ≤ .05, **p ≤ .01, ***p ≤ .001