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. 2021 Aug 20;17:2123–2163. doi: 10.3762/bjoc.17.138

Table 1.

Overview of the most significant polymers with LCST behavior ordered by the polymer arrangements star polymer, polymer micelles as well as polymers covalently grafted on nanoparticles and flat surfaces.

Polymer arrangements Polymer Object of research/highlighted application reference

star polymers [102103,106] PNIPAAm-based polymers [102]
PNIPAAm-PDEAEMA synthesis/analysis [141142]
PNIPAAm-PS synthesis/analysis [143]
PNIPAAm-PEG synthesis/analysis [108]
PEG-PDEAEMA-PNIPAAm synthesis/analysis [144]
PEG-PNIPAAm-Plys/PAA synthesis/analysis [145]
PS-PCL-PNIPAA synthesis/analysis [146]
PEG-PtBMA-PNIPAAm synthesis/analysis [147]
PS-PNIPAAm-PDMAEMA synthesis/analysis [148]
PNIPAAm-P4VP synthesis/analysis [149]
PS-PNIPAAm-P4VP synthesis/analysis [102,149]
PAA-PNIPAAm nanocarrier/molecule delivery; synthesis [105]
PCL-PNIPAAm nanocarrier/drug delivery, synthesis [150]
PTEGDA-PNIPAAm-PNMA drug delivery, synthesis [151]
PNASME-PNIPAAm synthesis/analysis [152]
POX-based star polymers
PBOX-PEtOX synthesis/analysis [153]
PEtOX- PIPOX synthesis/analysis [154]
PIPOX synthesis/analysis [155156]
PEG or PEG derivates-based star polymers
PEG-PDMAEMA synthesis/analysis [157]
PCL-POEOMA-PMEO2M synthesis/analysis [158]
PDEGA-PHEA synthesis/analysis [159]
P(DEGMA-OEGMA-GMA) as nanolayers for controlled cell sheet detachment, synthesis [160]
PDMAEMA-PDEGA synthesis/analysis [161]
other polymers
MPEP-PCL-PPE synthesis/analysis [162]
PVAc-PNVCL-PNVP synthesis/analysis [163]

polymer micelles [4,59,164165] PNIPAAm-based micelles
P4VP-PNIPAAm catalysis, synthesis [166]
PNIPAAm-PDMAAm drug delivery, synthesis [167]
PNIPAAm-DNA synthesis/analysis [168]
PNIPAAm-PHPMA-PEG synthesis/analysis [169]
PNIPAAm-PBMA drug delivery, synthesis [170]
PNIPAAm-PS synthesis/analysis [171172]
PNIPAAm-HPG [173]
POX-based micelles [174175]
PEtOX-PPropOX synthesis/analysis [176]
PIPOX-PAMPT radionuclide delivery, synthesis [177]
PMeOX-PIPOX-PBuO synthesis/analysis [178]
PBOX-PEtOX drug delivery, synthesis [153]
PMeOX-PBuOX synthesis/analysis [179]
other polymers
PDMAEMA-PCL drug delivery, synthesis [180]
PEGMA-PMMA-PDEAEMA synthesis/analysis [181]
PHPMA-PDEGMA drug delivery, synthesis [182]

polymers grafted on nanoparticles [4,115,117,164,183185] PNIPAAm-based grafted nanoparticles
PNIPAAm- preparation/analysis [186]
PDMAAm@Fe3O4 preparation/analysis [187]
PNIPAAm-PNHMA@ Fe3O4 drug release, preparation [188191]
PNIPAAm@SiO2 molecule delivery, preparation [191194]
PNIPAAm@Fe3O4 microfluidic separation and assay; sensing; drug release, preparation [195201]
PNIPAAm@Au fundamental investigation, preparation, cell up-take control [200,202]
PNIPAAm-PAm@Au PNIPAAm-PNVP@Fe3O4 cell up-take control drug delivery/cell separation, preparation [203]
PNIPAAm-PDMAEMA@Fe3O4/Au catalysis, preparation [204]
PNIPAAm-PAA@UCNP sensing, preparation [205]
PNIPAAm-PMAA-PVP@Fe2O3 drug delivery, preparation [206]
POX-based grafted nanoparticles [207]
PIPOX@Fe3O4 preparation/analysis [208]
PIPOX-PEtOX@SPION cell up-take control [209]
PEtOX/PPropOX-PVIm/P4VP@Ag preparation/analysis [210]
PEG or PEG derivates-based grafted nanoparticles [211]
PEG-PDMAEMA@Au preparation/analysis [212]
PEGMA@Au preparation/analysis [151,213]
PMEO2MA-OEGMA@Au protein adsorption, preparation [214]
PEGMA-PEG@SiO2 catalysis, preparation [215]
PEG-PPO@SPIO protein adsorption, preparation
sensing, contrast agent
[216]
PEG-PPO@ SiO2 drug delivery [217]
other polymers
P(HPEI-IBAm)@Au preparation/analysis [218219]
PVME@Au preparation/analysis [220]
PMDM@Au, glass or SiO2 catalysis, sensing, preparation [221223]
PTEGMMA-PMAPMA@SiO2 protein adsorption, preparation [224]

polymers grafted on flat surfaces [3,43,225226] PNIPAAm-based grafted surface [43,227]
PNIPAAm@different flat substrates, such as Au, Si-wafers, glass preparation, theory, fundamental investigation of swelling behavior, cell/protein adhesion, sensing, environmental application [132,228255]
PNIPAAm-PAA@SiO2 protein adhesion, preparation [256259]
PMMA-PBIEM-PNIPAAm cell up-take control, preparation [260]
PNIPAAm-PLAMA@glass preparation [261]
PNIPAAm-PDMAEMA@Al preparatio [262]
PNIPAAm-PNTBA@glass cell up-take control, preparation [263]
PNIPAAm-ODS@glass microfluidic, preparation [264]
PNIPAAm-PEG@Au cell up-take control, preparation [265]
POX-based grafted surface
PCPOX-PMeOX@SiO2 preparation [228]
PPropOX@glass cell up-take control, preparation [266]
PEG or PEG derivates-based grafted surfaces [43,211]
PMEO2MA-PDEAEMA@SiO2 preparation [267]
PMEO2MA-POEGMA@SiO2 protein adsorption, preparation [268]
other polymers
PMDM@glass protein adsorption, preparation [221]
PVCL-PDMAEMA-PMPC@PDMS controlled wettability
self-cleaning, anti-microbial coating, preparation
[269]