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. 2021 Aug 20;9:e11907. doi: 10.7717/peerj.11907

Table 4. Genotypic and allelic distributions of CMIP SNPs between SCZ patients and healthy controls stratified by different sex.

SNPs Genotype Female Male
Case Control χ 2 P P adj OR (95% CI) Case Control χ 2 P P adj OR (95% CI)
rs3751859 G/G–G/A 267 302 (89.1%) 0.111 0.784 0.824 1 386 (89.6%) 383 0.27 0.578 0.845 1
(89.90%) (88.50%)
A/A 30 37 0.931 [0.559–1.551] 45 (10.4%) 50 0.886 [0.577–1.358]
(10.10%) (10.90%) (11.60%)
Aelle
G 393 463 0.686 0.427 0.824 1 586(68%) 587 0 0.87 0.87 1
(66%) (68%) (68%)
A 201 215 1.100 [0.869–1.391] 276 279 0.983 [0.803–1.204]
(34%) (32%) (32%) (32%)
rs77700579 A/A-T/A 305 337 (99.4%) 0.241 0.659 0.824 1 428 (98.6%) 425 0.295 0.634 0.845 1
(99.70%) (98.20%)
T/T 1 2 1.718 [0.155–19.067] 6 8 1.297 [0.445–3.784]
(0.30%) (0.60%) (1.40%) (1.80%)
Aelle
A 556 613 0.072 0.824 0.824 1 782 766 1.217 0.271 0.733 1
(91% (90%) (90%) (88%)
T 56 65 1.044 [0.717–1.520] 86 100 1.187 [0.875–1.611]
(9%) (10%) (10%) (12%)
rs12925980 C/C–C/T 248 (82.9%) 283 (83.5%) 0.194 0.635 0.824 1 354 (82.3%) 367 0.044 0.847 0.87 1
(84.80%)
T/T 51 (17.1%) 56 (16.5%) 1.083 [0.780–1.504] 76 (17.7%) 66 1.028 [0.777–1.360]
(15.20%)
Aelle
C 402 348 0.158 0.691 0.824 1 726(87%) 760 0.434 0.515 0.845 1
(59%) (58%) (88%)
T 276 250 1.051 [0.840–1.314] 112 (13%) 108 1.066 [0.879–1.292]
(41%) (42%) (12%)
rs2287112 T/T–G/T 276 (96.2%) 335 (99.1%) 6.148 0.023 0.092 1 406 (96.9%) 426 (98.2%) 1.408 0.275 1
G/G 11 3 4.445 [1.227–16.105] 13 8 0.733 1.645 [0.674–4.019]
(3.80%) (0.90%) (3.10%) (1.80%)
Aelle
T 552 670 12.296 0.001 0.008* 1 812 852 2.816 0.122 0.733 1
(96.20%) (99.10%) (96.90%) (98.20%)
G 22 6 4.445 [1.788–11.046] 26 16 1.645 [0.875–3.094]
(3.80%) (0.90%) (3.10%) (1.80%)

Notes:

*

Represent Padj< 0.05.

Padj represent P corrected by FDR.

OR is abbreviation of Odds ratio, 95% CI is abbreviation of 95% confidence interval.