Table 8.

Summary of the results of the general linear model using WMH volumes and covariates as independent variables and cognitive scores and group diagnosis as dependent variables.

	Cognitive scores
	MMSE		ADAS-Cog		CDR sum		Group(CN/MCI/AD)
	β	p-value	β	p-value	β	p-value	β	p-value
WMH volume	−0.176	< 0.001**	0.133	0.017*	0.165	0.009**	0.131	0.008**
Age	–	–	–	–	–	–	–	–
CV risk	–	–	–	–	–	–	–	–
Education	0.062	< 0.001**	−0.061	0.001**	−0.047	0.031*	–	–
Gender	–	–	–	–	–	–	–	–
ApoE4 genotype	−0.296	< 0.001**	0.184	< 0.001**	0.421	< 0.001**	0.299	< 0.001**
Race	–	–	–	–	–	–	–	–

^*p-value corrected by FDR < 0.05.

^**p-value corrected by Bonferroni method < 0.05.