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. 2021 Aug 23;25(6):791–801. doi: 10.1007/s40291-021-00553-3

Table 2.

Parasitological and serological findings from congenital Chagas disease-infected infants during the follow-up

Patient ID Appointment Age Reference standard (ME or serology)a Index tests
LAMP qPCR QPCR (par. eq./mL)
015 T1 6 D Pos Pos Pos 706.2
032 T1 5 D Pos Pos Pos 23.6
037 T1 9 D Pos Pos Pos 347.8
042 T1 7.1 M Pos Pos Pos 4718.3
052 T1 39 D Neg Neg Pos NQ
T2 10.5 M Neg ND Pos 73.6
T2bis 19.2 M Pos ND Pos 7.8
053 T1 8 D Neg ND ND ND
T2 10.6 M Pos Pos Pos 2145.3
061 T1 17 D Neg Neg Pos NQ
T2 9.1 M Pos ND Pos 543.1
084 T1 53 D Pos Pos Pos 257.8
091 T1 4 D Pos Pos Pos 2058.3
101 T1 11 D Neg Neg Pos 27.5
T1bis 3.7 M Pos Pos Pos 3392.8
118 T1 29 D Pos Pos Pos 164.7
140 T1 84 D Pos Pos Pos 1698.0
141 T1 44 D Pos Neg Pos 320.0

D days, LAMP isothermal assay, M months, ME microscopic examination, ND not done, Neg no detectable parasites or non-reactive serology as appropriate, NQ not quantifiable (<0.5 par. eq./mL), par. eq./mL parasite equivalents per milliliter of blood, Pos detectable or reactive as appropriate, qPCR real-time PCR, QPCR quantitative PCR, T1 baseline, T2 after 9 months of age, T1bis and T2bis off-label appointments

aReference standard, ME at baseline (T1 and T1bis) and serology at 9 months old or more if ME was negative (T2 and T2bis)