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. 2021 Aug 23;16(8):e0256445. doi: 10.1371/journal.pone.0256445

Fig 2. Association of abundance of Gsp07 and G. swidsinskii/G. leopoldii with poor clinical response to metronidazole.

Fig 2

Abundance of all species of Gardnerella were determined at enrollment (1, open symbols) and as mean abundance of days 7–14 (M, closed symbols), per patient of clades by clinical outcome group. Ref = Refractory patients, Rec = Recurrent patients, Rem = Remission patients. Means and 95% CI’s are depicted. Comparing like days between outcome groups by ANOVA post-hoc Holm-Sidak, showed significant differences among Gsp07 abundance (only significant P values are shown); the arrow for G. swidsinskii/G. leopoldii comparisons indicates a significant downward trend. Paired t-tests for all 15 day 1 versus mean abundance of all clades showed no significant time-dependent changes.