Figure 2.

Dose–response effect of potassium chromate on the transmembrane potential of the HEK293H cells. (A) Bright-field microscope images (40×) of the HEK293H cells after 90 min K₂CrO₄ treatment with various concentrations. (B) Transmembrane potential of the HEK293H cells after the treatment of K₂CrO₄ with different concentrations. The average transmembrane potentials are untreated (−50.9 ± 2.48 mV), K₂CrO₄ [10 μM] (−39.6 ± 2.5 mV), K₂CrO₄ [100 μM] (−30.8 ± 1.2 mV), and K₂CrO₄ [500 μM] (−14.1 ± 4.5 mV). For statistics with N = 5: untreated vs 10 μM, “**” P < 0.01; 10 μM vs 100 μM, “***” P < 0.001; 100 μM vs 500 μM, “***” P < 0.001. Both optical images and transmembrane potential measurements were taken about 90 min after the treatment.