Table 17:
Additional Chemotherapy Cost Parameters
| Model Parameter | Mean | Reference |
|---|---|---|
| Mean number of cycles | 5 | Henricks et al, 201980 |
| Mean dose Intensitya | ||
| DPYD wild-type | 97% | Lunenburg et al, 20187 |
| DPYD carrier receiving standard dose | 91% | Lunenburg et al, 20187 |
| DPYD carrier receiving reduced dose | 61% | Lunenburg et al, 20187 |
Dose intensity is the amount of chemotherapy drugs received by the patient divided by the initial scheduled amount of chemotherapy.