Table 16:
Utilities Used in Economic Model
| Health State Utility | Mean (SE)a | Distribution (Parameters)a,b | Reference |
|---|---|---|---|
| Remission | 0.826 (0.065) | Beta (α: 27.272; β: 5.745) | Mrazek et al, 2013109 |
| No remission | 0.552 (0.120) | Beta (α: 8.928; β: 7.246) | Mrazek et al, 2013109 |
| Relapse | 0.417 (0.126) | Beta (α: 5.969; β: 8.344) | Mrazek et al, 2013109 |
| Disutility associated with medication side effects | –0.055 (0.03) | Beta (α: 3.121; β: 53.629) | Mrazek et al, 2013109,110 Najafzadeh et al, 201781 |
| Well (recovery)b | 0.940 (0.03) | Beta (α: 57.967; β: 3.700) | Lenert et al, 2000111 |
Abbreviation: SE, standard error.
a
Beta distributions were assigned in probabilistic analysis. Two parameters of the beta distribution (α, β) will be derived from the mean and SE (stated for each model parameter). Distribution parameter values were based on original data; further adjustments and transformations to the model cycle length of 1 month were performed.
b
Well health state was included in a scenario analysis only.