Table 1.
Comparison of demographic and hemodynamics parameters between POTS children with different responses to metoprolol.
| Items | Responders | Non-responders | Statistics | P value |
| Cases, n | 36 | 15 | – | – |
| Sex (M/F) | 21/15 | 7/8 | 0.206∗ | 0.650 |
| Age (years) | 12.0 ± 2.3 | 12.1 ± 2.1 | −0.195† | 0.847 |
| Height (cm) | 154.9 ± 14.4 | 158.2 ± 10.4 | −0.802† | 0.427 |
| Weight (kg) | 43.5 (40.0, 58.3) | 47.8 ± 13.6 | −0.207‡ | 0.836 |
| BMI (kg/m2) | 18.2 (16.7, 21.1) | 18.9 ± 3.6 | −0.434‡ | 0.664 |
| HR (bpm) | 78 ± 12 | 72 (65, 78) | −1.304‡ | 0.192 |
| SBP (mmHg) | 106 ± 13 | 104 ± 8 | 0.747† | 0.458 |
| DBP(mmHg) | 62 ± 10 | 61 ± 9 | 0.276† | 0.784 |
| ΔHR (bpm) | 48 (43, 52) | 48 ± 8 | −0.673‡ | 0.501 |
| HR max (bpm) | 126 ± 11 | 122 ± 11 | 1.360† | 0.180 |
| Pre-treatment SS (points) | 5 (3, 8) | 6 (4, 12) | −1.020‡ | 0.308 |
| Usg | 1.022 (1.017, 1.026) | 1.023 ± 0.007 | −0.777‡ | 0.437 |
∗χ2; †t; ‡Z. BMI: Body mass index; bpm: Beats per minute; DBP: Diastolic blood pressure; HR: Heart rate; ΔHR: HR increase from standing to the supine during 10 min; HR max: Maximum HR within 10 min of standing; POTS: Postural tachycardia syndrome; SS: Symptom scores; SBP: Systolic blood pressure; Usg: Urine specific gravity.